A study was conducted to determine whether cassava could provide the necessary support to increase seed yields of centro (Centrosema pubescens). The effect of centro on cassava tuber yield and the cost of production of centro seed under three production methods, i.e. unstaked, staked and supported by cassava, were determined. Results showed that centro twining on cassava yielded more seed than the unstaked one. It was slightly but significantly less than that of staked centro. Centro did not affect cassava tuber yield. Production costs of I kg of seed were Shs 1200, 2000 and 3700 for centro supported by cassava, unstaked and staked, respectively. It was concluded that centro seed could be easily and economically produced on a sustainable basis by small-scale farmers ::rowing cassava in Uganda.