Two novel bacteriophages that infectcausative agent of enteric septiccmia 01" catfish (LSC). were isolated from aquaculture pond watcr and rl"Om a diseased channel catlish. l30th phages «PeiDWF and produced clear plaques ranging 1"1'0111 0.5 to I I mm in diameter, and have an icosahedral head that is approximately 50 nm in diameter with a non-rigid tail structure. The phages are tentatively classilied in the ramily arc doubleI: stranded DNA viruses with approximate genome sizes of" 39 and 45 kb. respectively. wilh man) rest rict ion rragments in common as revea led by mult ip Ie restrict ion digests. Phage infection is calcium-dependent.